"Natural Born Killaz" is a collaborative single released by Dr. Dre and Ice Cube for the soundtrack of the film Murder Was the Case. It was originally intended for the scrapped N.W.A album 'Heltah Skeltah'.
The album song portrays a couple walking down the street in a bad neighborhood, until, from a distance, they are yelled at and verbally insulted by a local thug. Though the intro is different in the video and audio versions, both of them involve murder and end with the sound of a gunshot. The final shot of the video features a cameo from rapper and actor Tupac Shakur, prior to his association with Death Row Records, who poses as a SWAT sniper who takes out Ice Cube's character. Although the song and video were highly popular, and debuted a short time after release of the Oliver Stone film Natural Born Killers, the song did not appear in the film or on its soundtrack. It did, however, appear in the 2011 film Bridesmaids starring Kristen Wiig.