||It has been suggested that Polysporin be merged into this article. (Discuss) Proposed since February 2013.|
|Owner||Johnson & Johnson|
|Licence data||US FDA:|
|Legal status||OTC (US)|
|(what is this?)|
There is concern that use of Neosporin contributes to the emergence of antibiotic resistant bacteria. In the US, the only large market for Neosporin, the ointment has been shown to promote the prevalence of MRSA bacteria, specifically the highly lethal ST8:USA300 strain.
The original ointment contains three different antibiotics: bacitracin, neomycin, and polymyxin B, in a relatively low molecular weight patented base of cocoa butter, cottonseed oil, sodium pyruvate, tocopheryl acetate, and petroleum jelly.
The generic name for these products, regardless of the base, is "Triple Antibiotic Ointment". In China, this product is called "Complex Polymyxin B Ointment," which is manufactured by Zhejiang Reachall Pharmaceutical. The product was also marketed by The Upjohn Company under the name "Mycitracin", until 1997 when that name was acquired by Johnson & Johnson.
A "Plus" variant of the ointment exists that adds the analgesic pramoxine, but uses the cheap, simple, long-lasting, but heavier petroleum jelly base that is common to many OTC topicals. The latest version of this, a high-absorption cream, removes the bacitracin which is unstable in such a base, but keeps the analgesic.
One study showed no evidence that covering a small wound with Polysporin provided any benefit greater than that of simple petroleum jelly, while another study showed that minor wounds treated with Neosporin showed a "significantly" decreased rate of infection. Neosporin has been shown to cause contact dermatitis in some cases, and may contribute to antibiotic resistance.
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