Neuromedin N

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Neuromedin N[1]
Neuromedin N.svg
Identifiers
CAS number 102577-25-3 YesY
PubChem 3025353
IUPHAR ligand 1578
Jmol-3D images Image 1
Properties
Molecular formula C38H63N7O8
Molar mass 745.949
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY (verify) (what is: YesY/N?)
Infobox references
Neuromedin N
Identifiers
Symbol NN
Entrez 4922
HUGO 8038
Other data
Locus Chr. 12 q21

Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.[2][3][4][5][6][7]

References[edit]

  1. ^ Neuromedin N - Compound Summary, PubChem.
  2. ^ Carraway RE, Mitra SP, Spaulding G (1992). "Posttranslational processing of the neurotensin/neuromedin-N precursor". Annals of the New York Academy of Sciences 668 (1 The Neurobiol): 1–16. doi:10.1111/j.1749-6632.1992.tb27335.x. PMID 1463268. 
  3. ^ Kitabgi P, De Nadai F, Rovère C, Bidard JN (1992). "Biosynthesis, maturation, release, and degradation of neurotensin and neuromedin N". Annals of the New York Academy of Sciences 668 (1 The Neurobiol): 30–42. doi:10.1111/j.1749-6632.1992.tb27337.x. PMID 1463273. 
  4. ^ Vincent JP (October 1995). "Neurotensin receptors: binding properties, transduction pathways, and structure". Cellular and Molecular Neurobiology 15 (5): 501–12. doi:10.1007/BF02071313. PMID 8719037. 
  5. ^ Adams DH, Hanson GR, Keefe KA (2001). "Differential effects of cocaine and methamphetamine on neurotensin/neuromedin N and preprotachykinin messenger RNA expression in unique regions of the striatum". Neuroscience 102 (4): 843–51. doi:10.1016/S0306-4522(00)00530-3. PMID 11182247. 
  6. ^ Friry C, Feliciangeli S, Richard F, Kitabgi P, Rovere C (February 2002). "Production of recombinant large proneurotensin/neuromedin N-derived peptides and characterization of their binding and biological activity". Biochemical and Biophysical Research Communications 290 (4): 1161–8. doi:10.1006/bbrc.2001.6308. PMID 11811984. 
  7. ^ Kitabgi P (October 2006). "Differential processing of pro-neurotensin/neuromedin N and relationship to pro-hormone convertases". Peptides 27 (10): 2508–14. doi:10.1016/j.peptides.2006.03.038. PMID 16904237.