Nevis Labs is a research center owned and operated by Columbia University. It is located in Irvington, New York on the 60-acre (240,000 m2) property originally owned by Col.James Alexander Hamilton, the son of Alexander Hamilton, a graduate of Columbia College. James Hamilton built his mansion on this estate and named it Nevis in honor of the birthplace of his father.
The land was donated to the university by the DuPont family of Delaware. Construction of the physics facilities began in 1947 and by the 1950s it was home to the world's most powerful cyclotron. University president Dwight D. Eisenhower inaugurated the accelerator. It was decommissioned in 1976.
Currently the laboratory specializes in the preparation, design, and construction of high-energy particle and nuclear experiments and equipment. These are transported to major laboratories worldwide. The lab also performs data analysis for these experiments.
The laboratory is also home to the Radiological Research Accelerator Facility (RARAF) a National Institute of Biomedical Imaging and Bioengineering biotechnology resource center (P41) specializing in microbeam technology.