The premise behind the series, according to Larsen, is:
... for any fan of comics, not just fans of Golden Age books. Often, the promise of Golden Age comics—where creators were making up the rules as they went along and were blazing new trails—was more exciting than the reality..., where creators were essentially mimicking some of the same dull formulaic writing found in other mediums at the time. Everyone who contributes to [the Next Issue Project] was intent on fulfilling the promise of the Golden Age and delivering a book that was more than a mere homage, but also a thrilling glimpse of what comics could be—if only creators were allowed to run wild with the characters they were handed!
Each issue of the Next Issue Project utilizes features from a title published during the 1930s and 1940s period historians and fans call the Golden Age of Comic Books, with similar dimensions and page count, both larger than the modern-day standard. Each issue continues the name and numbering of each title.