|Born||citation needed]February 27, 1957 [|
|Alma mater||University of Leeds (undergraduate)
University of Dundee (postgraduate)
|Thesis||Studies on the hormone-sensitive adenylate cyclase from bovine corpus luteum (1982)|
|Notable awards||Lasker Clinical Award (2009)
Japan Prize (2012)
Fellow of the Royal Society (2013)
Nicholas B. Lydon FRS (born 27 February 1957) is a British scientist and entrepreneur. In 2009 he was awarded the Lasker Clinical Award and in 2012 the Japan Prize for the development of Gleevec, a selective BCR-ABL inhibitor for the treatment of chronic myeloid leukemia (CML); converting a fatal cancer into a manageable chronic condition. 
Lydon was educated at Strathallan School near Perth, Scotland. He earned a Bachelor of Science degree in biochemistry from the University of Leeds, England in 1978 and received his Ph.D in biochemistry from the University of Dundee, Scotland in 1982.
In 1982 Lydon accepted a position with Schering-Plough based in France as Charge de Recherche. Three years later he moved to Switzerland to work with Ciba-Geigy Pharmaceuticals, with whom he developed Gleevec. In 1997 he established Kinetex Pharmaceuticals in Boston which was acquired by Amgen in 2000, with whom he worked until 2002. Thereafter, he established several companies that continue to develop drugs to treat various conditions.
Honours and awards
- Warren Alpert Foundation Prize, 2000.
- Twenty First Annual AACR-Bruce F. Cain Memorial Award, 2002.
- Charles F. Kettering Prize, General Motors Cancer Research Foundation, 2002.
- The Lasker-DeBakey Clinical Medical Research Award, with Brian Druker and Charles Sawyers, 2009.
- Doctor of Laws honoris causa, University of Dundee, 2011.
- The Japan Prize, with Brian Druker and Janet Rowley, 2012.
- Fellow of the Royal Society, 2013.
- Royal Society GlaxoSmithKline Prize and Lecture, 2014 
- "Nicholas Lydon". ScienceHeroes.com. 2010. Retrieved 13 February 2013.
- "Lasker - DeBakey Clinical Medical Research Award: Award Description". Lasker Foundation. Retrieved 16 August 2010.
- "Laureates of the Japan Prize". The Japan Prize Foundation. 2012. Retrieved 13 February 2013.
- Druker, B. J.; Talpaz, M.; Resta, D. J.; Peng, B.; Buchdunger, E.; Ford, J. M.; Lydon, N. B.; Kantarjian, H.; Capdeville, R.; Ohno-Jones, S.; Sawyers, C. L. (2001). "Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia". New England Journal of Medicine 344 (14): 1031–1037. doi:10.1056/NEJM200104053441401. PMID 11287972.
- List of publications from Microsoft Academic Search
- Druker, B. J.; Tamura, S.; Buchdunger, E.; Ohno, S.; Segal, G. M.; Fanning, S.; Zimmermann, J.; Lydon, N. B. (1996). "Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells". Nature medicine 2 (5): 561–566. doi:10.1038/nm0596-561. PMID 8616716.
- Buchdunger, E.; Cioffi, C. L.; Law, N.; Stover, D.; Ohno-Jones, S.; Druker, B. J.; Lydon, N. B. (2000). "Abl protein-tyrosine kinase inhibitor STI571 inhibits in vitro signal transduction mediated by c-kit and platelet-derived growth factor receptors". The Journal of pharmacology and experimental therapeutics 295 (1): 139–145. PMID 10991971.
- "Dr Nicholas Lydon". University of Dundee. 2011. Retrieved 13 February 2013.
- Lydon, Nicholas B. (1982). Studies on the hormone-sensitive adenylate cyclase from bovine corpus luteum (PhD thesis). University of Dundee.(subscription required)
- "Dr Nicholas Lydon". The Royal Society. 2013. Retrieved 29 May 2013.
- "GlaxoSmithKline prize". Royal Society. Retrieved 12 September 2013.
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