Nicholas Charles Tyrwhitt Wheeler (born 20 January 1965 in Ludlow, Shropshire) is an English businessman. He attempted a number of different businesses, including a photography venture and a Christmas tree delivery service. In 1986 he established the Charles Tyrwhitt company and shirt brand, which he owns.
Wheeler grew up in Ludlow and was educated at the Dragon School in Oxford, Eton College, and the University of Bristol, where he studied geography. His first job was as a management consultant for Bain & Company. In November 1986, he set up Charles Tyrwhitt, now a well-known shirt brand in the United Kingdom. The business is a Limited Liability Partnership. It has grown to be the UK’s largest mail-order shirt business, and also has several brick and mortar locations (as of October 2014, 17 in the United Kingdom, 5 in the United States, and one in France). 
In 2008, he was a regional judge for the Entrepreneur Challenge in the UK.
- Andrew Davidson, Nick Wheeler, founder of Charles Tyrwhitt. The Sunday Times, Business section, 13 December 2009. Published as 'The old Etonian barrow boy', page 6 (paper version).
- Charles Tyrwhitt History, Charles Tyrwhitt, UK.
- "Nick Wheeler: From failed photographer to Jermyn Street's king of the shirts". London: Independent. 15 October 2009.
- Nick Wheeler of Charles Tyrwhitt Shirts says that work should be fun, The Sunday Times, Business section, 23 March 2008.
- Nick Wheeler and Chrissie Rucker, Rich List 2009, The Sunday Times, 26 April 2009.
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