Nijō Mitsuhira (二条 光平?, 1624 – 1682), son of Nijō Yasumichi, was a Japanese kugyō (court noble) of the early Edo period. He held regent positions kampaku from 1653 to 1663 and sesshō from 1663 to 1664. Nijō Tsunahira was his adopted son. A daughter of his was a consort of the third head of Kōfu Domain Tokugawa Tsunashige.
- ネケト. 二条家（摂家） (in Japanese). Retrieved 2007-09-14.
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