Skoufas was born in 1779 in the village of Kompoti near Arta. He worked at various times as an apothecary, a commercial secretary and a hatter. Skoufas left as a merchant for Russia for business purposes. While there, he became acquainted with Athanasios Tsakalov and Emmanuil Xanthos. The three men came up with the idea of founding a secret organisation to prepare the ground for Greek independence. So, the Filiki Eteria was founded in 1814 in Odessa. Skoufas dedicated the rest of his life to the cause. For this purpose he went to Moscow but his ideas did not meet with the approval of many people of the local Greek community.
In 1818, the three partners moved to Constantinople to further their cause, but in July of that same year Skoufas fell ill and died.
- Ioannis Michaletos (2006-09-28). "Freemasonry in Greece: Secret History Revealed". Balkanalysis.com. Retrieved May 2009.
- Phillips, W. Alison (1897). The war of Greek independence, 1821 to 1833. London : Smith, Elder. pp. 20, 21. (retrieved from University of California Library)
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