From Wikipedia, the free encyclopedia
Jump to: navigation, search
IUPAC name
ATC code A02BA05
84845-75-0 YesY
ChEMBL ChEMBL1909284 N
ChemSpider 11644617 N
EC number 284-304-0
Jmol-3D images Image
KEGG D07072 YesY
MeSH C073716
PubChem 3033952
Molar mass 434.50924
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Niperotidine is a histamine antagonist selective for the H2 subtype. It was trialled as a treatment for excessive gastric acidity,[1] but withdrawn after human trials showed liver damage.[2]


  1. ^ Palasciano G, Maggi V, Portincasa P. The effect of the H2-antagonist niperotidine on intragastric acidity in healthy subjects undergoing 24-hour pH-monitoring. Italian Journal of Gastroenterology. 1990 Oct;22(5):291-4. PMID 1983712
  2. ^ Gasbarrini G, Gentiloni N, Febbraro S, Gasbarrini A, Di Campli C, Cesana M, Miglio F, Miglioli M, Ghinelli F, D'Ambrosi A, Amoroso P, Pacini F, Salvadori G. Acute liver injury related to the use of niperotidine. Journal of Hepatology. 1997 Sep;27(3):583-6. PMID 9314138