Nisoldipine

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Nisoldipine
Nisoldipine.png
Systematic (IUPAC) name
isobutyl methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Clinical data
Trade names Sular
AHFS/Drugs.com monograph
MedlinePlus a696009
  • US: C (Risk not ruled out)
Oral
Pharmacokinetic data
Protein binding 99%
Half-life 7-12 hours
Identifiers
63675-72-9 YesY
C08CA07
PubChem CID 4499
IUPHAR ligand 2524
DrugBank DB00401 N
ChemSpider 4343 N
UNII 4I8HAB65SZ N
KEGG D00618 YesY
ChEBI CHEBI:7577 N
ChEMBL CHEMBL1726 N
Chemical data
Formula C20H24N2O6
388.414 g/mol
 N (what is this?)  (verify)

Nisoldipine (INN) is a calcium channel blocker of the dihydropyridine class. It sold in the United States under the proprietary name Sular. Nisoldipine has tropism for cardiac blood vessels. [1]

External links[edit]

References[edit]

  1. ^ http://www.sciencedirect.com/science/article/pii/S0002914999804469; Why is nisoldipine a specific agent in ischemic left ventricular dysfunction?