Nitarsone

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Nitarsone
Nitarsone.svg
Names
IUPAC name
(4-Nitrophenyl)arsonic acid
Other names
(p-Nitrophenyl)arsonic acid; 4-Nitrobenzenearsonic acid
Identifiers
ChemSpider 60190
Jmol-3D images Image
PubChem 66826
Properties
C6H6AsNO5
Molar mass 247.04 g·mol−1
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Nitarsone is an organoarsenic compound that is used in poultry production as a feed additive to increase weight gain, improve feed efficiency, and prevent blackhead disease.[1] It is marketed as Histostat by Zoetis, a publicly traded subsidiary of Pfizer.[2]

Nitarsone is one of four arsenical animal drugs approved by the U.S. Food and Drug Administration for use in poultry, along with roxarsone, arsanilic acid, and carbarsone.[3] Following the 2011 suspension of roxarsone sales in the United States, however, it is believed to be the only arsenical animal drug currently marketed in the U.S.[3][4] In September 2013, the FDA announced that Zoetis and Fleming Laboratories would voluntarily withdraw current roxarsone, arsanilic acid, and carbarsone approvals, leaving only nitarsone approvals in place.[5] When the withdrawals occur, nitarsone will be the only arsenical approved for use in food animals in the U.S.


References[edit]

  1. ^ U.S. Food and Drug Administration. "Animal Drugs @ FDA". 
  2. ^ Zoetis. "Histostat: Type A Medicated Feed Article". 
  3. ^ a b U.S. Food and Drug Administration (June 8, 2011). "Questions and Answers Regarding 3-Nitro (Roxarsone)". 
  4. ^ Sabrina Tavernise (May 11, 2013). "Study Finds an Increase in Arsenic Levels in Chicken". New York Times. 
  5. ^ U.S. Food and Drug Administration (September 20, 2011). "FDA Response to Citizen Petition on Arsenic-based Animal Drugs".