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IUPAC name
(E)-N-(6-Chloro-3-pyridylmethyl)- N-ethyl-N'-methyl-2-nitrovinylidenediamine
Other names
ATCvet code QP53BX02
150824-47-8 YesY
ChemSpider 2298774 N
Jmol-3D images Image
KEGG C18511 YesY
UNII 3A837VZ81Y YesY
Molar mass 270.72 g/mol
Melting point 72 °C (162 °F; 345 K)[1]
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Nitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of livestock and pets. It is a neonicotinoid, a neurotoxin that blocks neural messages in the central nervous system of insects, causing rapid death.

It is used orally with dogs and cats to control fleas. After ingestion, it begins killing fleas within 30 minutes and kills all adult fleas within 4 hours. The effects of nitenpyram last approximately 24–48 hours. Nitenpyram is safe to use on puppies and kittens as young as four weeks old if they weigh at least 2 pounds (0.91 kg). Panting and excitement have been noted in cats within 2 hours of administration. In heavily infested animals, it can cause extreme itching as the fleas die.

Nitenpyram does not kill insect eggs and has no long-term activity. Thus, it is not effective as a long-term flea preventative. It is usually used to kill nymph and adult fleas quickly on an infested animal, and combined with a longer-term flea preventative like fipronil or lufenuron to prevent reinfestation.

External links[edit]


  1. ^ Safety (MSDS) data for nitenpyram