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|Molar mass||270.72 g/mol|
|Melting point||72 °C|
| (what is: / ?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
In veterinary medicine, it is used orally with dogs and cats to control fleas. After ingestion, the manufacturers claim it may start killing fleas within 30 minutes and kills adult flea on the pet within 4 hours. The effects of nitenpyram last approximately 24–48 hours. Nitenpyram is safe to use on puppies and kittens as young as four weeks old so long as they weigh at least 2 pounds (0.91 kg). Panting and excitement have been noted in cats within 2 hours of Capstar administration.
Nitenpyram is a neonicotinoid, which means that it is a neurotoxin that blocks the ability for neural messages to transmit through the central nervous system of the flea causing (almost) instant death.
It has no long-term residual activity and therefore is not effective as a longer-term flea preventative. It is usually used to kill adult fleas quickly on an infested animal to give immediate relief for a day. It is then usually followed up with some other longer-term flea preventative to prevent reinfestation. In heavily infested animals, it can cause extreme itching as the fleas die; this almost always resolves on its own.
It is often used as part of the protocol in treating environmental infestations.
- Capstar website
- Material Safety Data Sheet (MSDS) for Nitenpyram
- Freedom of Information summary (NADA 141-053), US Food and Drug Administration
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