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CAS number 133-58-4 YesY
PubChem 16682935
ChemSpider 16739372
Jmol-3D images Image 1
Molecular formula C7H5HgNO3
Molar mass 351.71 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Nitromersol (metaphen) is a mercury-containing organic compound that is primarily used as an antiseptic and disinfectant. It has no odor or taste and is stored as a brown-yellow granules or powder. Nitromersol does not irritate the skin or mucous membranes and has no impact on rubber or metallic instruments, including surgical and dental tools.[1]

This compound is a confirmed animal carcinogen. It can emit toxic fumes of NOx and mercury when destroyed by heat.[2] In 1998, use of nitromersol (and other mercury-containing products) as OTC first-aid antiseptics and products for diaper rash and vaginal contraceptives was outlawed by the FDA.[3] Nitromersol can cause hypersensitivity reactions, but it is still in use as a preservative for vaccines and antitoxins.[4]


  1. ^ Hospital formulary and compendium of useful information. Berkeley, California: University of California Press. 1941. p. 113. Retrieved 2011-04-08. 
  2. ^ Lewis, Richard J. (2008). Hazardous chemicals desk reference. Wiley-Interscience. p. 1018. ISBN 0-470-18024-2. Retrieved 2011-04-08. 
  3. ^ Remington: the science and practice of pharmacy. Medicine Series 1 (21st ed.). Lippincott Williams & Wilkins. 2005. p. 369. ISBN 0-7817-4673-6. 
  4. ^ Trevor, Anthony J.; Katzung, Bertram G.; Masters, Susan B. (2007). Katzung & Trevor's pharmacology: examination & board review. Lange Basic Science (8th ed.). McGraw-Hill Professional. p. 420. ISBN 0-07-148869-3.