Non-specific serine/threonine protein kinase
|Non-specific serine/threonine protein kinase|
|PDB structures||RCSB PDB PDBe PDBsum|
In enzymology, the term non-specific serine/threonine protein kinase (EC 18.104.22.168) describes a class of enzymes that belong to the family of transferases, specifically protein-serine/threonine kinases. These enzymes transfer phosphates to the oxygen atom of a serine or threonine sidechain in proteins. This process is called phosphorylation. Protein phosphorylation in particular plays a significant role in a wide range of cellular processes and is a very important posttranslational modification.
The chemical reaction performed by these enzymes can be written as
- ATP + a protein ADP + a phosphoprotein
The systematic name of this enzyme class is ATP:protein phosphotransferase (non-specific).
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