Nooglutyl

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Nooglutyl
Nooglutyl.svg
Identifiers
CAS number 112193-35-8
PubChem 147523
ChemSpider 130090
Jmol-3D images Image 1
Properties
Molecular formula C11H12N2O6
Molar mass 268.22 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Nooglutyl is a nootropic agent being studied at the Research Institute of Pharmacology, Russian Academy of Medical Sciences as a potential treatment for amnesia.[1]

In animal models, it has a variety of central nervous system effects.[2][3][4][5]

References[edit]

  1. ^ Flekhter, Oxana B. (2000). "Nooglutil, Russian Academy of Medical Science". Current Opinion in Central & Peripheral Nervous System Investigational Drugs 2 (4): 491–497. 
  2. ^ V. V. Yasnetsov, V. A. Pravdivtsev, V. M. Popov, T. A. Voronina, N. M. Kiseleva and S. B. Kozlov (May 1995). "Antimotion Effect of Nooglutyl and Its Neuronal Mechanism". Bulletin of Experimental Biology and Medicine 119 (5): 515–516. doi:10.1007/BF02543440. PMID 7579248. Retrieved 2011-02-08. 
  3. ^ Voronina, TA; Borlikova, GG; Garibova, TL; Proskuryakova, TV; Petrichenko, OB; Burd, SG; Avakyan, GN (2002). "Effect of nooglutil on benzodiazepine withdrawal syndrome and binding of 3H-spiperone with D2 receptors in rat striatum". Bulletin of experimental biology and medicine 134 (5): 448–50. PMID 12802448. 
  4. ^ Garibova, TL; Galaeva, IP; Voronina, TA; Kraĭneva, VA; Kapitsa, IG; Kirichenko, SV; Makarenko, AN; Mirzoian, GR; Kuznetsova, EA (2003). "Effect of nooglutil on rats with intracerebral posttraumatic hematoma (hemorrhagic stroke)". Eksperimental'naia i klinicheskaia farmakologiia 66 (3): 13–6. PMID 12924225. 
  5. ^ Povarova, OV; Garibova, TL; Kalenikova, EI; Galaeva, IP; Kraĭneva, VA; Medvedev, OS; Voronina, TA (2004). "Effect of phenyl-tert-butylnitrone, mexidol and nooglutil on the ischemic lesion zone and memory in rats following middle cerebral artery occlusion". Eksperimental'naia i klinicheskaia farmakologiia 67 (1): 3–6. PMID 15079898.