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Systematic (IUPAC) name
Clinical data
Legal status
CAS number 561-48-8
ATC code None
PubChem CID 22391
ChemSpider 21015
Synonyms Herchst 10495, NIH-7557
Chemical data
Formula C23H29NO 
Mol. mass 335.483 g/mol

Norpipanone (INN, BAN; Hexalgon) is an opioid analgesic related to methadone which was developed in Germany and distributed in Hungary, Argentina, and other countries.[1][2] It had originally not been under international control but upon observation of case reports of addiction it was reviewed and shortly thereafter became a controlled substance.[1][2] In the United States, it is a Schedule I controlled substance (ACSCN 9636, zero annual manufacturing quota as of 2013)


Norpipanone synthesis:[3]

See also[edit]


  1. ^ a b John B Buckingham (December 1995). Dictionary of Organic Compounds. CRC Press. p. 2883. ISBN 978-0-412-54090-5. Retrieved 11 May 2012. 
  2. ^ a b David S. Patterson (12 March 2002). Foreign Relations of the United States, 1961-1963, Volume XXV: Organization of Foreign Policy; Information Policy; United Nations; Scientific Matters. Government Printing Office. pp. 766–767. ISBN 978-0-16-050885-1. Retrieved 11 May 2012. 
  3. ^ Dupr�, D. J. (1949). "113. Analgesics. Part I. Esters and ketones derived from ?-amino-?-cyano-??diarylalkanes". Journal of the Chemical Society (Resumed): 500. doi:10.1039/JR9490000500.  edit