Norton Zinder
| Norton Zinder | |
|---|---|
Marilyn Zinder, Norton Zinder and Esther M. Lederberg, Feb. 1972 |
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| Born | Norton David Zinder November 7, 1928 New York City, New York |
| Died | February 3, 2012 (aged 83) New York City, New York |
| Fields | Microbiology |
| Institutions | Rockefeller University |
| Alma mater | University of Wisconsin–Madison |
| Known for | Transduction Virology |
| Notable awards | NAS Award in Molecular Biology (1966) |
Norton David Zinder (November 7, 1928 – February 3, 2012) was an American biologist famous for his discovery of genetic transduction. Zinder was born in New York City, received his Ph.D. from the University of Wisconsin–Madison, and became a member of the National Academy of Sciences in 1969. He led a lab at Rockefeller University until shortly before his death.
In 1966 he was awarded the NAS Award in Molecular Biology from the National Academy of Sciences.[1]
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[edit] Genetic transduction and RNA bacteriophage
Working as a graduate student with Joshua Lederberg, Zinder discovered that bacteriophage can carry genes from one bacterium to another. Initial experiments were carried out using Salmonella. Zinder and Lederberg named this process of genetic exchange transduction.
Later, Zinder discovered the first bacteriophage that contained RNA as its genetic material. At that time, Harvey Lodish of the Massachusetts Institute of Technology worked in his lab.[2]
He died in 2012 of pneumonia after a long illness.[3]
[edit] References
- ^ "NAS Award in Molecular Biology". National Academy of Sciences. http://www.nasonline.org/site/PageServer?pagename=AWARDS_molbio. Retrieved 27 February 2011.
- ^ Lodish, H. F.; Zinder, N. D. (1966). "Replication of the RNA of Bacteriophage f2". Science 152 (3720): 372–377. doi:10.1126/science.152.3720.372. PMID 17775172.
- ^ [1]
[edit] Further reading
- Lederberg, J.; Zinder, N. (1948). "Concentration of biochemical mutants of bacteria with penicillin". Journal of the American Chemical Society 70 (12): 4267. PMID 18105993.
- Lederberg, J.; Lederberg, E. M.; Zinder, N. D.; Lively, E. R. (1951). "Recombination analysis of bacterial heredity". Cold Spring Harbor symposia on quantitative biology 16: 413–443. PMID 14942753.
- Zinder, N. D.; Lederberg, J. (1952). "Genetic Exchange in Salmonella". Journal of bacteriology 64 (5): 679–699. PMC 169409. PMID 12999698. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=169409.
- Kresge, N.; Simoni, R. D.; Hill, R. L. (2011). "The Molecular Genetics of Bacteriophage: The Work of Norton Zinder". The Journal of biological chemistry 286 (25): e4–e5. PMC 3121416. PMID 21830328. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3121416.
- Nicolas Wade: Norton D. Zinder, Researcher in Molecular Biology, Dies at 83. In: The New York Times. February 7, 2012.