The music video features a restaurant employee, played by the same actor who appeared in the video for Mötley Crüe's "You're All I Need", washing dishes while listening to the Kiss hit single "Rock and Roll All Nite", performed by Poison. The manager enters, turns off the radio, and delivers to the employee a scathing reprimand, reminding the employee that he is being paid "to wash dishes, not to listen to that... that rock 'n' roll," and accusing him of "moving in two speeds: slow, and stop." The manager exits, whereupon the employee abandons the dishes and kicks open a nearby door to reveal a concert hall stage, upon which the band then performs the song. When the song is over, the manager returns, discovering, to his surprise, that all the dishes are washed.
"Nothin' but a Good Time" was performed by Poison, with the cast of Rock of Ages, at the 63rd Tony Awards on June 7, 2009. After the performance, as the band made their way backstage, a piece of the stage scenery collapsed on Bret Michaels.
In The Simpsons season 11 episode "It's a Mad, Mad, Mad, Mad Marge", Otto hires a Poison tribute band called Cyanide to play this song at his wedding. However, the band can only play the intro before Otto's fiancé, Becky, stops them.
The song is played in the movie Yogi Bear when Yogi and Boo-Boo water ski, and in the Regular Show episode "My Mom", when the song is played during a montage sequence where Mordecai, Rigby, High-Five Ghost and Muscle Man blow off work.
The song, plus two other Poison songs are downloadable for Rock Band 3.