Nucleolar phosphoprotein p130

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Nucleolar and coiled-body phosphoprotein 1
Symbols NOLC1 ; NOPP130; NOPP140; NS5ATP13; P130
External IDs OMIM602394 MGI1918019 HomoloGene68818 GeneCards: NOLC1 Gene
RNA expression pattern
PBB GE NOLC1 205895 s at tn.png
PBB GE NOLC1 211949 s at tn.png
PBB GE NOLC1 211951 at tn.png
More reference expression data
Species Human Mouse
Entrez 9221 70769
Ensembl ENSG00000166197 ENSMUSG00000015176
UniProt Q14978 E9PVC9
RefSeq (mRNA) NM_001284388 NM_001039351
RefSeq (protein) NP_001271317 NP_001034440
Location (UCSC) Chr 10:
103.91 – 103.92 Mb
Chr 19:
46.08 – 46.09 Mb
PubMed search [1] [2]

Nucleolar phosphoprotein p130 is a protein that in humans is encoded by the NOLC1 gene.[1][2][3]


Nucleolar phosphoprotein p130 has been shown to interact with Coilin[4] and CEBPB.[5]


  1. ^ Pai CY, Chen HK, Sheu HL, Yeh NH (Oct 1995). "Cell-cycle-dependent alterations of a highly phosphorylated nucleolar protein p130 are associated with nucleologenesis". J Cell Sci. 108. ( Pt 5): 1911–20. PMID 7657714. 
  2. ^ Chen HK, Pai CY, Huang JY, Yeh NH (Jan 2000). "Human Nopp140, which interacts with RNA polymerase I: implications for rRNA gene transcription and nucleolar structural organization". Mol Cell Biol 19 (12): 8536–46. PMC 84972. PMID 10567578. 
  3. ^ "Entrez Gene: NOLC1 nucleolar and coiled-body phosphoprotein 1". 
  4. ^ Isaac, C; Yang Y; Meier U T (Jul 1998). "Nopp140 functions as a molecular link between the nucleolus and the coiled bodies". J. Cell Biol. (UNITED STATES) 142 (2): 319–29. doi:10.1083/jcb.142.2.319. ISSN 0021-9525. PMC 2133063. PMID 9679133. 
  5. ^ Miau, L H; Chang C J; Shen B J; Tsai W H; Lee S C (Apr 1998). "Identification of heterogeneous nuclear ribonucleoprotein K (hnRNP K) as a repressor of C/EBPbeta-mediated gene activation". J. Biol. Chem. (UNITED STATES) 273 (17): 10784–91. doi:10.1074/jbc.273.17.10784. ISSN 0021-9258. PMID 9553145. 

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