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Nwoya District is a district in Northern Uganda. Like most districts in Uganda, it is named after its main municipal, administrative and commercial center, Nwoya, the location of the district headquarters.
Nwoya District is bordered by Amuru District to the north, Gulu District to the northeast, Oyam District to the east, Kiryandongo District, Masindi District and Buliisa District to the south. Nebbi District lies to the west of Nwoya District. Nwoya, the main political, administrative and commercial center in the district, is located approximately 44 kilometres (27 mi), by road, southwest of the city of Gulu, the largest metropolitan area in the sub-region. This location is approximately 330 kilometres (210 mi), by road, north of the city of Kampala, Uganda's capital and largest metropolitan area.  The coordinates of the district are:02 38N, 32 00E.
Nwoya District is one of the newest districts in Uganda. It was established by Act of Parliament and began functioning on 1 July 2010. Prior to that date, it was part of Amuru District. The district is part of the Acholi sub-region, together with:
In 2002, the population of Nwoya District was recorded at approximately 41,010. As of December 2010[update], the exact population of the district is unknown.