From Wikipedia, the free encyclopedia
OPIE may refer to:
- Open Palmtop Integrated Environment, a free user interface for palm top computers
- One Time Passwords in Everything, a framework that allows to use one-time passwords in Unix
- Opie and Anthony, an American radio show duo
- Opie Gets Laid, a Vivendi Entertainment romantic comedy film
- Opie Taylor, a television character portrayed by Ron Howard on The Andy Griffith Show
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