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Olfactory receptor, family 1, subfamily A, member 1
Symbols OR1A1 ; OR17-7
External IDs MGI1333770 HomoloGene8219 GeneCards: OR1A1 Gene
RNA expression pattern
PBB GE OR1A1 221388 at tn.png
More reference expression data
Species Human Mouse
Entrez 8383 258706
Ensembl ENSG00000172146 ENSMUSG00000070377
UniProt Q9P1Q5 Q7TRX1
RefSeq (mRNA) NM_014565 NM_146711
RefSeq (protein) NP_055380 NP_666922
Location (UCSC) Chr 17:
3.12 – 3.12 Mb
Chr 11:
74.21 – 74.21 Mb
PubMed search [1] [2]

Olfactory receptor 1A1 is a protein that in humans is encoded by the OR1A1 gene.[1][2]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]

See also[edit]


  1. ^ Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D (Apr 2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. 
  2. ^ a b "Entrez Gene: OR1A1 olfactory receptor, family 1, subfamily A, member 1". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.