OR1D4

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Olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene)
Identifiers
Symbols OR1D4 ; OR17-30
External IDs HomoloGene55761 GeneCards: OR1D4 Gene
Orthologs
Species Human Mouse
Entrez 653166 n/a
Ensembl ENSG00000255095 n/a
UniProt P47884 n/a
RefSeq (mRNA) NM_003552 n/a
RefSeq (protein) NP_003543 n/a
Location (UCSC) Chr 17:
3.14 – 3.14 Mb
n/a
PubMed search [1] n/a

Olfactory receptor 1D4 is a protein that in humans is encoded by the OR1D4 gene.[1][2][3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

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References[edit]

  1. ^ Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H et al. (Jul 1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum Mol Genet 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID 8004088. 
  2. ^ Glusman G, Sosinsky A, Ben-Asher E, Avidan N, Sonkin D, Bahar A, Rosenthal A, Clifton S, Roe B, Ferraz C, Demaille J, Lancet D (Apr 2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. 
  3. ^ a b "Entrez Gene: OR1D4 olfactory receptor, family 1, subfamily D, member 4". 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.