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Olfactory receptor, family 2, subfamily AE, member 1
Symbols OR2AE1 ; OR2AE2
External IDs MGI3030004 HomoloGene128272 GeneCards: OR2AE1 Gene
RNA expression pattern
PBB GE OR2AE1 gnf1h11267 at tn.png
More reference expression data
Species Human Mouse
Entrez 81392 258959
Ensembl ENSG00000244623 ENSMUSG00000062245
UniProt Q8NHA4 n/a
RefSeq (mRNA) NM_001005276 NM_146957
RefSeq (protein) NP_001005276 NP_667168
Location (UCSC) Chr 7:
99.47 – 99.47 Mb
Chr 16:
19.52 – 19.52 Mb
PubMed search [1] [2]

Olfactory receptor 2AE1 is a protein that in humans is encoded by the OR2AE1 gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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Further reading[edit]

  • "Toward a complete human genome sequence.". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074. 
  • Thompson EE, Kuttab-Boulos H, Yang L et al. (2006). "Sequence diversity and haplotype structure at the human CYP3A cluster.". Pharmacogenomics J. 6 (2): 105–14. doi:10.1038/sj.tpj.6500347. PMID 16314882. 

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.