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Olfactory receptor, family 8, subfamily B, member 12
Symbols OR8B12 ; OR11-317
External IDs MGI3030708 HomoloGene17377 GeneCards: OR8B12 Gene
Species Human Mouse
Entrez 219858 258882
Ensembl ENSG00000170953 ENSMUSG00000063350
UniProt Q8NGG6 D3Z5L8
RefSeq (mRNA) NM_001005195 NM_146882
RefSeq (protein) NP_001005195 NP_667093
Location (UCSC) Chr 11:
124.41 – 124.41 Mb
Chr 9:
37.75 – 37.75 Mb
PubMed search [1] [2]

Olfactory receptor 8B12 is a protein that in humans is encoded by the OR8B12 gene.[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.