OX40L is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. OX40L has also been designated [1 ] CD252 ( cluster of differentiation 252).
Various single nucleotide polymorphisms (SNPs) of the OX40L gene have been identified. For some of them association with
systemic lupus erythematosus has been reported: No association with occurrence of atherosclerosis has been found. [2 ] [3 ]
References [ edit ]
^ Maizels RM, Yazdanbakhsh M (2003). "Immune regulation by helminth parasites: cellular and molecular mechanisms" (PDF). Nat. Rev. Immunol. 3 (9): 733–44. doi: 10.1038/nri1183. PMID 12949497.
^ Lu MM (Jul 2013). "Association of TNFSF4 polymorphisms with systemic lupus erythematosus: a meta-analysis.". Mod Rheumatol 23 (4): 686–93. doi: 10.3109/s10165-012-0708-8. PMID 22850862.
^ Huang Q (Apr 2014). "Absence of association between atherosclerotic cerebral infarction and TNFSF4/TNFRSF4 single nucleotide polymorphisms rs1234313, rs1234314 and rs17568 in a Chinese population.". J Int Med Res 42 (2): 436–43. doi: 10.1177/0300060514521154. PMID 24595151.
External links [ edit ]