The name originated in the Basque Country and means "wolf" in the Basque language (spelled otsoa or otxoa in Standard Basque). There was also a female given name Ochanda (meaning "female wolf", cf. the elegant tower in the old quarter of Vitoria-Gasteiz named after Ochanda, proper name of the daughter of a man responsible for revamping the tower in the 16th century) and Ochotorena or Otxotorena, meaning "son of Ochoto' (lit. small wolf). The Spanish version of this Basque given name was Lope, also appearing in the names of Gascon lords in the High Middle Ages.
The name may refer to:
- Alex Ochoa (1972–), American baseball player
- Arnaldo Ochoa (1930–1989), Cuban army general, executed for treason
- Baltazar Hinojosa Ochoa (1930–), Mexican politician, mayor of Matamoros, Tamaulipas
- Carla Ochoa (1979–), Chilean fashion model
- Carlos Ochoa (1978–), Mexican football (soccer) player
- Digna Ochoa (1964–2001), Mexican human-rights lawyer
- Eduardo López Ochoa (1877–1936), Spanish army general, Africanist, and Freemason
- Eliades Ochoa (1946–), Cuban guitarist and singer
- Ellen Ochoa (1958–), first Mexican-American astronaut
- Estevan Ochoa (1831–1888), Mexican-born American businessman and politician
- Eugenio de Ochoa (1815–1872), Spanish author and translator
- Fabio Ochoa Restrepo (a.k.a. "Don Fabio") (1923–2002), Colombian businessman, father of the Ochoa brothers
- Francisco Fernández Ochoa (1950–2006), Spanish alpine skier
- Francisco Labastida Ochoa (1942–), Mexican economist and politician
- Gorka Otxoa (1979–), Spanish actor
- Guillermo Ochoa (a.k.a. "Paco Memo") (1985–), Mexican football (soccer) player
- Israel Ochoa (1964–), Colombian cyclist
- Javier Otxoa (1974–), Spanish cyclist
- Jesús Ochoa (footballer) (1981–), Mexican-American football (soccer) player
- Jesús Ochoa (actor) (1959–), Mexican actor
- Ochoa brothers, former members of the Medellín drug cartel. Jorge Ochoa and his brothers Juan David and Fabio.
- Leire Martínez Ochoa (1979–), Spanish-Basque singer, vocalist of La Oreja de Van Gogh after Amaia Montero's departure
- Lewis Ochoa (1991-), English football (soccer) player
- Lorena Ochoa (1981–), Mexican golfer
- Paquito Ochoa, Jr. (1960-), Filipino lawyer and politician
- Mariana Ochoa (1979–), Mexican actress and singer
- Miguel Ochoa, a fictional detective in the Nikki Heat novel series.
- Raymond Ochoa (2001–), American actor and brother of Ryan Ochoa.
- Richard Ochoa (1984–), Venezuelan track and road cyclist
- Ryan Ochoa (1996–), American actor
- Rolando Ochoa (1916-2009), Highly successful actor and stand-up comedian in Cuban radio, television and theater.
- Samuel Ochoa (1986-), Mexican football (soccer) player
- Severo Ochoa (1905–1993), Spanish biochemist, Nobel Laureate, Medicine, 1959
- Pablo Belisario Ochoa, one of the five genetic fathers of Agent 47 in the Hitman series
- Julio Ochoa, incumbent mayor of Liberty City in Grand Theft Auto IV
- Ochoa syndrome, rare congenital syndrome associated with facial expressions and hydronephrosis
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