The station was opened on 9 January 1910 as part of the connecting section of the line under the Seine between Châtelet and Raspail. The line 10 platforms opened on 14 April 1926 as part of the line's extension from Mabillon. It was the eastern terminus of the line until its extension to Place d'Italie (now on line 7) on 15 February 1930. Named after the nearby Odéon theatre, the station is located under the Carrefour de l'Odéon, in the 6th arrondissement of Paris. The platforms on Line 4 were opened on 9 January 1910 and the platforms on Line 10 were opened on 14 February 1926.