Odessa is an unincorporated community in Klamath County, Oregon, United States. Odessa is located along Oregon Route 140 a few miles east of its interchange with the West Side Road near Rocky Point or 23 miles west of Klamath Falls. Odessa lies along Odessa Creek and was founded in the 1890s as a resort and Indian trading post. A post office operated in Odessa from 1902 thru 1919.
Currently the name is shared by the Odessa Store, the Odessa Ranch, and the USFS' Odessa Creek Campground.