Of Mice and Men is an opera in three acts by the American composer Carlisle Floyd. The English libretto was written by Floyd and is based on the novella of the same name by John Steinbeck. The opera was composed in 1969.
Of Mice and Men was first performed on January 22, 1970 by the Seattle Opera at the Moore Theater. The opera has been performed frequently within the United States. In 2004, Albany Records produced a recording of the opera. The opera is included for performance in the 2011 Opera Australia season and is directed by Australian film director Bruce Beresford.Sarasota Opera presented it in 2013.