Ohio State Route 49
Route of SR 49 highlighted in red
|Maintained by ODOT|
|Length:||153.34 mi (246.78 km)|
|Existed:||1926 – present|
|South end:||US 35 in Dayton|
| I‑70 in Dayton
I‑80 / I‑90 / Ohio Tpk. near Columbia
|North end:||M‑49 near Cooney|
|Counties:||Montgomery, Miami, Darke, Mercer, Van Wert, Paulding, Defiance, Williams|
State Route 49 (SR 49, Ohio 49) is a state highway in the western part of the U.S. state of Ohio. It begins at Drexel with US 35 and runs northwesterly to Greenville, and then runs roughly along near the western edge of the state near the Indiana state line to the Michigan state line where it meets with Michigan's M-49.
State Route 49's southern terminus is west of Dayton, at the intersection of U.S. Route 35 and West Third Street in Drexel. Both Drexel (a census-designated place) and the intersection straddle the border between Trotwood and Montgomery County's Jefferson Township. The roadway carrying SR 49 continues southward (signed "east") from this intersection as US 35 (designated "C. J. McLin Jr. Parkway"), a limited-access expressway into downtown Dayton. (Westbound US 35 proceeds along West Third Street.) Prior to 2000, SR 49 followed Salem Avenue to a southern terminus in downtown Dayton.
SR 49 continues north from US 35 through Trotwood along a roadway locally called the "Northwest Connector" or the "Trotwood Connector", then turns onto Salem Avenue, which crosses into Clayton. The route then briefly travels through Englewood, straddles the Englewood-Clayton line, again crosses into Clayton, then the ramps to and from Interstate 70 cross into Englewood and back into Clayton. SR 49 is then concurrent with I-70 for approximately 1.5 miles through Clayton. SR 49 then exits from I-70 at ramps passing from Clayton into Clay Township, Montgomery County. The route then continues north to Greenville, Fort Recovery, Willshire, Convoy, Payne, Antwerp, Hicksville, Edgerton and Edon. SR 49 then interchanges with the Ohio Turnpike at that highway's first interchange east of the Indiana-Ohio state line. SR 49 terminates at the Ohio-Michigan state line where it continues north as Michigan State Highway 49.