Iohexol
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| Systematic (IUPAC) name | |
| 1-N,3-N-bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodobenzene-1,3-dicarboxamide | |
| Clinical data | |
| AHFS/Drugs.com | Micromedex Detailed Consumer Information |
| Pregnancy cat. | B (US) |
| Legal status | ℞ Prescription only |
| Routes | Intrathecal, intravascular, oral, intracavital |
| Pharmacokinetic data | |
| Protein binding | Low |
| Metabolism | Nil |
| Half-life | Variable |
| Excretion | Renal, unchanged |
| Identifiers | |
| CAS number | 66108-95-0  |
| ATC code | V08AB02 |
| PubChem | CID 3730 |
| DrugBank | DB01362 |
| ChemSpider | 3599 |
| UNII | 4419T9MX03 |
| KEGG | D01817 |
| ChEBI | CHEBI:31709 |
| ChEMBL | CHEMBL1200455  |
| Chemical data | |
| Formula | C19H26I3N3O9 |
| Mol. mass | 821.138 g/mol |
| SMILES | eMolecules & PubChem |
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Iohexol is a contrast agent, sold under the trade name Omnipaque. It is available in various concentrations, from 140 to 350 milligrams of iodine per milliliter. Omnipaque 350 is commonly used as a contrast agent during coronary angiography.
The osmolality of iohexol ranges from 322 mOsm/kg—approximately 1.1 times that of blood plasma—to 844 mOsm/kg, almost three times that of blood.[1] Despite this difference, iohexol is still considered a low-osmolality contrast agent; the osmolality of older agents, such as diatrizoate, may be more than twice as high.[2]
[edit] References
- ^ GE Healthcare (May 2006). "Omnipaque (Iohexol) injection. Product label". DailyMed. U.S. National Library of Medicine. http://dailymed.nlm.nih.gov/dailymed/fdaDrugXsl.cfm?id=3465&type=display. Retrieved 2007-03-28.
- ^ Amersham Health (April 2006). "Hypaque (Diatrizoate Meglumine and Diatrizoate Sodium) injection, solution. Product label". DailyMed. U.S. National Library of Medicine. http://dailymed.nlm.nih.gov/dailymed/fdaDrugXsl.cfm?id=997&type=display. Retrieved 2007-03-29.
[edit] External links
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