Omphalotus subilludens
| Omphalotus subilludens | |
|---|---|
_H.E._Bigelow_590967.jpg)
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Scientific classification 
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| Domain: | Eukaryota |
| Kingdom: | Fungi |
| Division: | Basidiomycota |
| Class: | Agaricomycetes |
| Order: | Agaricales |
| Family: | Omphalotaceae |
| Genus: | Omphalotus |
| Species: | O. subilludens
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| Binomial name | |
| Omphalotus subilludens (Murrill) H.E. Bigelow 1982
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| Synonyms | |
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Clitocybe subilludens (Murrill) Murrill 1945[1]
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Omphalotus subilludens is a fungus species in the genus Omphalotus. The type collection was found by Murrill on July 26, 1944, in Gainesville, Florida. It has also been recorded from Texas. [1]
Atromentin and thelephoric acid are chemical compounds found in cultures of C. subilludens.[2] Atromentin is an effective anticoagulant, and similar in biological activity to the well-known anticoagulant heparin.[3] Atromentin also possesses antibacterial activity, inhibiting the enzyme enoyl-acyl carrier protein reductase (essential for the biosynthesis of fatty acids) in the bacteria Streptococcus pneumoniae.[4]
It also produces illudoids.[5]
References
- ^ Murrill, W.A., 1945, Quarterly Journal of the Florida Academy of Science 8(2): 198
- ^ Sullivan, G.; Garrett, R. D.; Lenehan, R. F. (1971). "Occurrence of atromentin and thelephoric acid in cultures ofclitocybe subilludens". Journal of Pharmaceutical Sciences. 60 (11): 1727–9. doi:10.1002/jps.2600601134. PMID 4332377.
- ^ Khanna JM, Malone MH, Euler KL, Brady LR (1965). "Atromentin – anticoagulant from Hydnellum diabolus". Journal of Pharmaceutical Sciences. 54 (7): 1016–20. doi:10.1002/jps.2600540714. PMID 5862512.
- ^ Zheng CJ, Sohn MJ, Kim WG (2006). "Atromentin and leucomelone, the first inhibitors specific to enoyl-ACP reductase (FabK) of Streptococcus pneumoniae". Journal of Antibiotics. 59 (12): 808–12. doi:10.1038/ja.2006.108. PMID 17323650.
- ^ Illudoids from Omphalotus olivascens and Clitocybe subilludens. Nair M. S. R., Carey S. T. and Rogerson C. T., Mycologia, 1983, vol. 75, no5, pages 920-922, INIST 9415717
External links