The conference sermons focus on prayer, evangelism, and Christian eschatology, preceded by long times of worship. The conference was initially inspired when Paul Cain, a former associate of International House of Prayer leadership, claimed to have a spiritual experience in which he saw thousands of young people gathering in Kansas City. In addition to theological instruction, the speakers often deliver inspirational messages on themes such as living a life without regrets. The sessions often include long periods of prayer for the United States, sometimes lasting until midnight. A particular emphasis is given to prayer for colleges and college students. The attendees numbered over 25,000 in 2010. Most attendees are young adults. More recent, Matt Redman has agreed to lead worship in Onething 2013.
Speakers and worship leaders have included:
- Mike Bickle
- Loren Cunningham
- Misty Edwards
- Lou Engle
- Jason Upton
- Matt Redman
- Francis Chan
- Jesus Culture
- Banning Liebscher
International House of Prayer has published 5 Onething Conference Albumswhich records the live worship music written by ihopkc worship leaders. For example, Cory Asbury, Laura Hackett, Matt Gilman, Misty Edwards and more.
- "Resuscitating spiritual passion `New breed' of pastors relies less on formal training and more on Jesus". The Washington Times. 6 July 2001. Retrieved 9 February 2011.
- LeClaire, Jennifer (28 December 2010). "25,000 Young Adults Gather at International House of Prayer Conference". Charisma. Retrieved 9 February 2011.
- "Sermon Notes". Onething 2010. International House of Prayer. Retrieved 10 February 2011.
- "Thousands Of Teens Come To KC To Pray". KMBC (Kansas City, MO). 31 December 2002. Retrieved 10 February 2011.
- Vu, Michelle (30 December 2010). "IHOP Founder Tells 27,000 Young Adults: Have No Regrets". The Christian Post. Retrieved 10 February 2011.
- Trent Sheppard; Pete Greig (2009). God on Campus: Sacred Causes & Global Effects. Downers Grove, IL: IVP Books. p. 158. ISBN 978-0-8308-3631-4. Retrieved 10 February 2011.
- Szczepanski, Carolyn (31 December 2008). "IHOPers converge to discuss the end of the world". The Pitch (Kansas City, MO). Retrieved 10 February 2011.
- Bickle, Mike (2009). After God's Own Heart. Charisma House. p. vii. ISBN 978-1-59979-530-0.
- "Channel Surfing". Charisma. 30 November 2007. Retrieved 26 February 2011.
- "Album - Forerunner Music". Kansas City, MO. Retrieved 28 June 2013.