Open research is research conducted in the spirit of free and open source software. Much like open source schemes that are built around a source code that is made public, the central theme of open research is to make clear accounts of the methodology freely available via the internet, along with any data or results extracted or derived from them. This permits a massively distributed collaboration, and one in which anyone may participate at any level of the project.
Types of open projects 
Important distinctions exist between different types of open projects.
Projects that provide open data but don't offer open collaboration are referred to as "open access" rather than open research. Providing open data is a necessary but not sufficient condition for open research, because although the data may be used by anyone, there is no requirement for subsequent research to take place openly. For example, though there have been many calls for more open collaborative research in drug discovery and the open deposition of large amounts of data, there are very few active, openly collaborative projects in this area.
Projects on the Internet that recruit large numbers of participants to carry out small tasks which are then assembled into a larger project outcome have delivered significant research outcomes, but these projects are distinct from those in which participants are able to influence the overall direction of the research, or in which participants are expected to have creative input into the science behind the project.
Most open research is conducted within existing research groups. Primary research data are posted which can be added to, or interpreted by, anyone who has the necessary expertise and who can therefore join the collaborative effort. Thus the "end product" of the project (which may still be subject to future expansion or modification) arises from many contributions across multiple research groups, rather than the effort of one group or individual. Open research is therefore distinct from open access in that the output of open research is prone to change with time.
Copyright conventions 
Issues with copyright are dealt with by using either standard copyright (where applicable), releasing the content into the Public domain or by releasing the content under licenses such as one of the Creative Commons licenses or one of the GNU General Public Licenses.
Science and engineering research to support the creation of open source appropriate technology for sustainable development has long used open research principles. Open source research for sustainable development is now becoming formalized with open access for literature reviews, research methods, data, results and summaries for laypeople.
While first attempts towards opening research were primarily aimed at opening areas such as scientific data, methodologies, software and publications, now increasingly other artifacts of the scientific workflow are also tackled, such as scientific meta-data and funding ideas.
See also 
- Open access (publishing)
- Open Data
- Open education
- Open Innovation
- Open science
- Open Notebook Science
- Open peer review
- Science 2.0
- Science Commons
- For an overview, see "Reinventing Discovery" by Michael Nielsen, Princeton University Press (October 21, 2011), ISBN 0-691-14890-2
- Open Science is a Research Accelerator, M. Woelfle, P. Olliaro and M. H. Todd, Nature Chemistry 2011, 3, 745-748
- Mission Possible, A. L Hopkins, M. J Witty, S. Nwaka Nature 2007, 449, 166-9
- F. -J. Gamo, et al. Thousands of chemical starting points for antimalarial lead identification. Nature 2010, 465, 305-310
- Open Source Drug Discovery wiki
- Indian Open Source Drug Discovery portal
- Mendeley Group on Open Source Drug Discovery
- S. Cooper, et al. Predicting protein structures with a multiplayer online game. Nature 2010 466, 756-760
- K. Land et al. Galaxy Zoo: the large-scale spin statistics of spiral galaxies in the Sloan Digital Sky Survey, Mon. Not. R. Astron. Soc. 2008, 388, 1686-1692
- Article on open access and open research in Chemistry
- The Synaptic Leap
- MIAWiki for Open Research and Collaboration
- Article in the American Chemical Society's magazine C&E News on Open Research
- Article in Australian Journal of Chemistry on The Synaptic Leap
- Article on The Synaptic Leap project in schistosomiasis from Nature
- Amy Kapczynski et al., “Addressing Global Health Inequities: An Open Licensing Approach for University Innovations,” Berkley Technology Law Journal 20 (2005): 1031–1114.
- Stephen M. Maurer, Arti Rai, and Andrej Sali, "Finding Cures for Tropical Diseases: Is Open Source an Answer?", PLoS Medicine 1, no. 3 (December 2004): 183–186.
- Joshua M. Pearce, “The Case for Open Source Appropriate Technology”, Environment, Development and Sustainability, 14, pp. 425-431 (2012). http://dx.doi.org/10.1007/s10668-012-9337-9
- A. J. Buitenhuis, I. Zelenika and J. M. Pearce, “Open Design-Based Strategies to Enhance Appropriate Technology Development”, Proceedings of the 14th Annual National Collegiate Inventors and Innovators Alliance Conference : Open, March 25–27th 2010, pp. 1–12.
- Grue, Amanda J. An investigation into and recommendations for appropriate technology education. MIT. 2011. open access
- Joshua M. Pearce, “Open Source Research in Sustainability”, Sustainability: the Journal of Record, 5(4), pp. 238-243, 2012. DOI free and open access
- Main Page - OpenResearch.org
- Auer, S.; Braun-Thürmann, H.: Towards Bottom-Up, Stakeholder-Driven Research Funding - Open Source Funding, Open Peer Review. In Peer Review Reviewed: The International Career of a Quality-control Instrument and New Challenges 24–25 April 2008, Social Science Research Center Berlin (WZB), Berlin.