Together with left-hemisphere BA 45, the left hemisphere BA 44 comprises Broca's area a region involved in semantic tasks. Some data suggest that BA44 is more involved in phonological and syntactic processing. Some recent findings also suggest the implication of this region in music perception. Recent neuroimaging studies show BA44 involvement in selective response suppression in go/no- go tasks and is therefore believed to play an important role in the suppression of response tendencies. Neuroimaging studies also demonstrate that area 44 is related to hand movements.
Scott Flansburg of San Diego, California is a "human calculator" who can perform complex arithmetic in his head. Profiled on the TV show Stan Lee's Superhumans, his brain was scanned using fMRI while doing complex calculations, which showed brain activity in this region was absent. Instead there was activity somewhat higher from area 44 and closer to the motor cortex.
^Forstmann, Birte U.; Van den Wildenberg, Wery P.M. and Ridderinkhof, Richard K (2008). Neural Mechanisms, Temporal Dynamics, and Individual Differences in Interference Control. Journal of Cognitive Neuroscience 20:10, pp. 1854-65.