Optochin

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Optochin
Optochin.png
Names
IUPAC name
(4β,8α,9R)-6'-Ethoxy-10,11-dihydrocinchonan-9-ol
Other names
Ethylhydrocupreine
Identifiers
522-60-1 YesY
ChEMBL ChEMBL534999 N
ChemSpider 79283 N
Jmol-3D images Image
MeSH Optochin
PubChem 71542
Properties
C21H28N2O2
Molar mass 340.46 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Optochin (or ethylhydrocupreine) is a chemical used in cell culture techniques for the presumptive identification of Streptococcus pneumoniae, which is optochin-sensitive, from other alpha-hemolytic streptococci such as Streptococcus viridans, which are resistant. A common mnemonic is "OVRPS" (Optochin - Viridans [are] Resistant, Pneumoniae [are] Sensitive). Or "VROPS" (Viridans Resistant [to] Optochin, Pneumoniae Sensitive)

The growth of bacteria that are optochin-sensitive will be inhibited around an optochin disc, while the growth of bacteria that are optochin-resistant will not be affected. In vitro, a solution of as little as 1:10,000,000 may be inhibitory to the pneumococcus, and 1:500,000 is bactericidal.[1]

Resistance[edit]

Strains of Streptococcus pneumoniae have been found to be resistant to optochin in laboratory testing.[2]

References[edit]