Osamu Hayaishi

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Osamu Hayaishi
Native name 早石 修
Born (1920-01-08)January 8, 1920
Stockton, California
Nationality Japanese
Fields Biochemistry
Institutions Osaka Bioscience Institute
Osaka Medical College
Kyoto University
Vanderbilt University
University of Tokyo
Osaka University
Washington University in St. Louis
National Institutes of Health
Alma mater Osaka University
Doctoral students Yasutomi Nishizuka
Tasuku Honjo
Known for Oxygenases
Notable awards Wolf Prize in Medicine
Japan Academy Prize
Order of Culture
Asahi Prize (1964)

Osamu Hayaishi (早石 修 Hayaishi Osamu?, born January 8, 1920) is a Japanese biochemist and a professor at Osaka Bioscience Institute.[1]


Hayaishi was born in Stockton, California, U.S.A, in 1920. He completed his M.D. from Osaka University in 1942. He became professor at various universities in Japan and the US, and led about 600 graduate students in his life. More than 100 his pupils became professors at various universities in Japan.[2]

He was President of International Union of Biochemistry and Molecular Biology from 1973 to 1976.[3]


Hayaishi is known for his contributions to biomedical sciences and enzymology by his discovery of Oxygenases. These enzymes are widely distributed in nature and represent a unique group of respiratory enzymes that catalyze the direct incorporation of molecular oxygen into various substrates.

Citing his "outstanding and pioneering contributions to biomedical sciences and enzymology," the Wolf Foundation awarded Hayaishi the 1986 Wolf Prize in Medicine "for his discovery of the oxygenase enzymes and elucidation of their structure and biological importance".[4] [5]


  1. ^ Osamu Hayaishi at Osaka Biocience Institute
  2. ^ "運・鈍・根 酸素添加酵素と睡眠" Biography of Osamu Hayaishi(Japanese)
  3. ^ Hayaishi, Osamu (2006). "Memoirs of a biochemist". IUBMB Life (International Union of Biochemistry and Molecular Biology: Life) 58 (5-6): 242–245. doi:10.1080/15216540600702271. ISSN 1521-6543. 
  4. ^ "The 1986 Wolf Foundation Prize in Medicine". Wolf Foundation. Retrieved May 12, 2014. 
  5. ^ The Wolf Prize in Medicine

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