Óscar Fabián Murillo Murillo (born 18 April 1988 in Armenia) is a Colombian footballer who currently plays for Atlético Nacional.
Murillo began his career in the youth system of famed Argentinian side Boca Juniors. In 2007 he returned to Colombia to play for second division side Centauros Villavicencio. In 2008 he joined his hometown side Deportes Quindío and became a regular starter. His play with Quindío led to interest from foreign sides, particularly from Major League Soccer. He was signed on loan by Colorado Rapids in February 2010. His loan was terminated in July, 2010 without Murillo making a single league appearance. On February 20, 2012, he played for Atlético Nacional and scored twince in their win against Millonarios FC.