Osmophobia (oz′mō-fō′bē-ă, from Greek ὀσμή - osmē, "smell, odour" and φόβος - phobos, "fear") or olfactophobia (from Latin olfacto, "to smell at") refers to a fear, aversion, or psychological hypersensitivity to odors. The phobia generally occurs in chronic migraine sufferers who may have odor triggered migraines. Such migraines are most frequently triggered by foul odors, but the hypersensitivity may extend to all odors. One study found as many as 25% of migraine sufferers had some degree of osmophobia.
Some migraineurs treat their migraines with some success using pleasant odors, such as mint or lavender.
- ὀσμή, Henry George Liddell, Robert Scott, A Greek-English Lexicon, on Perseus
- φόβος, Henry George Liddell, Robert Scott, A Greek-English Lexicon, on Perseus
- olfacto, Charlton T. Lewis, Charles Short, A Latin Dictionary, on Perseus
- Bolen DW, Baskakov IV (2001). "The osmophobic effect: natural selection of a thermodynamic force in protein folding". Journal of Molecular Biology 27: 955–963. PMID 11502004.
- Kelman L (November 2004). "The place of osmophobia and taste abnormalities in migraine classification: a tertiary care study of 1237 patients". Cephalalgia 24 (11): 940–6. doi:10.1111/j.1468-2982.2004.00766.x. PMID 15482356.
- Kelman L (2004). "Osmophobia and taste abnormality in migraineurs: a tertiary care study". Headache 44 (10): 1019–23. doi:10.1111/j.1526-4610.2004.04197.x. PMID 15546266.
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