Oxaloacetate tautomerase

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oxaloacetate tautomerase
Identifiers
EC number 5.3.2.2
CAS number 37318-45-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an oxaloacetate tautomerase (EC 5.3.2.2) is an enzyme that catalyzes the chemical reaction

keto-oxaloacetate \rightleftharpoons enol-oxaloacetate

Hence, this enzyme has one substrate, keto-oxaloacetate, and one product, enol-oxaloacetate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting keto- and enol-groups. The systematic name of this enzyme class is oxaloacetate keto---enol-isomerase. This enzyme is also called oxalacetic keto-enol isomerase.

While oxaloacetate tautomerase was characterized in several papers in the 1960s and 1970's, this activity has not been correlated with any gene identified in the genome of higher organisms.

References[edit]

  • Annett RG, Kosicki GW (1969). "Oxalacetate keto-enol tautomerase. Purification and characterization". J. Biol. Chem. 244 (8): 2059–67. PMID 5781999.