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Chemical structure of the 5-(4H)-oxazolone isomer

Oxazolone is a chemical compound with the molecular formula C3H3NO2. There are three isomers according to the location of the carbonyl group and two more according to the location of the double bound C=X (with X=N or C):

  • 2-(3H)oxazolone.
  • 2-(5H)oxazolone.
  • 4-(5H)-oxazolone.
  • 5-(2H)-oxazolone.
  • 5-(4H)-oxazolone.

The oxazolone derivative 4-ethoxymethylene-2-phenyloxazol-5-one (a derivative of the 5-(4H)-oxazolone)is a chemical allergen used for immunological experiments, particularly for experiments on delayed type hypersensitivity.[1]

Chemical structure of 4-ethoxymethylene-2-phenyloxazol-5-one

See also[edit]


  1. ^ Nakano, Y (2004). "Stress-induced modulation of skin immune function: Two types of antigen-presenting cells in the epidermis are differentially regulated by chronic stress". The British journal of dermatology 151 (1): 50–64. doi:10.1111/j.1365-2133.2004.05980.x. PMID 15270872.