Oxidative deamination
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Oxidative deamination is a form of deamination that generates oxoacids in the liver.
The presence of nitrous acid can cause transition mutations, by converting cytosine to uracil. Primarily occurs in the liver and kidneys.[1][2]
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[edit] In Urea cycle
Glutamate is the only amino acid that undergoes rapid oxidative deamination by using glutamate dehydrogenase which uses NAD or NADP as a coenzyme. This process leads to two distinct toxic compounds:
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