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Systematic (IUPAC) name
Clinical data
Legal status ?
ATC code ?
PubChem CID 11099
ChemSpider 10628
Synonyms 4-Hydroxynorephedrine
Chemical data
Formula C9H13NO2 
Mol. mass 167.21 g/mol

p-Hydroxynorephedrine, or 4-hydroxynorephedrine, is the para-hydroxy analog of norephedrine and an active sympathomimetic metabolite of amphetamine in humans.[1][2] When it occurs as a metabolite of amphetamine, it is produced from both p-hydroxyamphetamine and norephedrine.[2][3][4]

See also[edit]


  1. ^ "p-Hydroxynorephedrine". NCBI. PubChem Compound. Retrieved 25 October 2013. 
  2. ^ a b "Adderall XR Prescribing Information". Medication Guide. United States Food and Drug Administration. Retrieved 7 October 2013. 
  3. ^ "Amphetamine: Biomedical Effects and Toxicity". NCBI. Pubchem Compound. Retrieved 12 October 2013. 
  4. ^ Santagati NA, Ferrara G, Marrazzo A, Ronsisvalle G (September 2002). "Simultaneous determination of amphetamine and one of its metabolites by HPLC with electrochemical detection". J. Pharm. Biomed. Anal. 30 (2): 247–55. doi:10.1016/S0731-7085(02)00330-8. PMID 12191709. 

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