The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y.
Ota T, Suzuki Y, Nishikawa T et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet.36 (1): 40–5. doi:10.1038/ng1285. PMID14702039.CS1 maint: Explicit use of et al. (link)
Fujiwara S, Yamashita Y, Choi YL et al. (2007). "Transforming activity of purinergic receptor P2Y, G protein coupled, 8 revealed by retroviral expression screening.". Leuk. Lymphoma48 (5): 978–86. doi:10.1080/10428190701225882. PMID17487742.CS1 maint: Explicit use of et al. (link)
Storlazzi CT, Albano F, Lo Cunsolo C et al. (2007). "Upregulation of the SOX5 by promoter swapping with the P2RY8 gene in primary splenic follicular lymphoma.". Leukemia21 (10): 2221–5. doi:10.1038/sj.leu.2404784. PMID17554380.CS1 maint: Explicit use of et al. (link)