PACSIN2

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Protein kinase C and casein kinase substrate in neurons 2
Protein PACSIN2 PDB 3ABH.png
Rendering based on PDB 3ABH.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols PACSIN2 ; SDPII
External IDs OMIM604960 MGI1345153 HomoloGene21414 GeneCards: PACSIN2 Gene
RNA expression pattern
PBB GE PACSIN2 201651 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 11252 23970
Ensembl ENSG00000100266 ENSMUSG00000016664
UniProt Q9UNF0 Q9WVE8
RefSeq (mRNA) NM_001184970 NM_001159509
RefSeq (protein) NP_001171899 NP_001152981
Location (UCSC) Chr 22:
43.23 – 43.41 Mb
Chr 15:
83.38 – 83.46 Mb
PubMed search [1] [2]

Protein kinase C and casein kinase substrate in neurons protein 2 is a protein that in humans is encoded by the PACSIN2 gene.[1][2][3]


Interactions[edit]

PACSIN2 has been shown to interact with PACSIN1,[2][4] PACSIN3[2] and Fas ligand.[5]

References[edit]

  1. ^ Ritter B, Modregger J, Paulsson M, Plomann M (Aug 1999). "PACSIN 2, a novel member of the PACSIN family of cytoplasmic adapter proteins". FEBS Lett 454 (3): 356–62. doi:10.1016/S0014-5793(99)00830-3. PMID 10431838. 
  2. ^ a b c Modregger J, Ritter B, Witter B, Paulsson M, Plomann M (Jan 2001). "All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis". J Cell Sci. 113 Pt 24: 4511–21. PMID 11082044. 
  3. ^ "Entrez Gene: PACSIN2 protein kinase C and casein kinase substrate in neurons 2". 
  4. ^ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  5. ^ Ghadimi, Markus Philipp; Sanzenbacher Ralf; Thiede Bernd; Wenzel Jennifer; Jing Qian; Plomann Markus; Borkhardt Arndt; Kabelitz Dieter; Janssen Ottmar (May 2002). "Identification of interaction partners of the cytosolic polyproline region of CD95 ligand (CD178)". FEBS Lett. (Netherlands) 519 (1–3): 50–8. doi:10.1016/S0014-5793(02)02709-6. ISSN 0014-5793. PMID 12023017. 

Further reading[edit]