PARC (gene)

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Cullin 9
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols CUL9 ; H7AP1; PARC
External IDs OMIM607489 MGI1925559 HomoloGene56696 GeneCards: CUL9 Gene
RNA expression pattern
PBB GE PARC 213204 at tn.png
PBB GE PARC 213871 s at tn.png
More reference expression data
Species Human Mouse
Entrez 23113 78309
Ensembl ENSG00000112659 ENSMUSG00000040327
UniProt Q8IWT3 E9QLV9
RefSeq (mRNA) NM_015089 NM_001081335
RefSeq (protein) NP_055904 NP_001074804
Location (UCSC) Chr 6:
43.15 – 43.19 Mb
Chr 17:
46.5 – 46.55 Mb
PubMed search [1] [2]

Cullin-9 is a protein that in humans is encoded by the CUL9 gene.[1][2][3][4]


PARC (gene) has been shown to interact with P53.[3]


  1. ^ Skaar JR, Florens L, Tsutsumi T, Arai T, Tron A, Swanson SK, Washburn MP, DeCaprio JA (Mar 2007). "PARC and CUL7 form atypical cullin RING ligase complexes". Cancer Res 67 (5): 2006–14. doi:10.1158/0008-5472.CAN-06-3241. PMID 17332328. 
  2. ^ Moynihan TP, Ardley HC, Nuber U, Rose SA, Jones PF, Markham AF, Scheffner M, Robinson PA (Nov 1999). "The ubiquitin-conjugating enzymes UbcH7 and UbcH8 interact with RING finger/IBR motif-containing domains of HHARI and H7-AP1". J Biol Chem 274 (43): 30963–8. doi:10.1074/jbc.274.43.30963. PMID 10521492. 
  3. ^ a b Nikolaev AY, Li M, Puskas N, Qin J, Gu W (Jan 2003). "Parc: a cytoplasmic anchor for p53". Cell 112 (1): 29–40. doi:10.1016/S0092-8674(02)01255-2. PMID 12526791. 
  4. ^ "Entrez Gene: PARC p53-associated parkin-like cytoplasmic protein". 

Further reading[edit]