PCDH10

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Protocadherin 10
Identifiers
Symbols PCDH10 ; OL-PCDH; PCDH19
External IDs OMIM608286 MGI1338042 HomoloGene74967 GeneCards: PCDH10 Gene
RNA expression pattern
PBB GE PCDH10 gnf1h00367 s at tn.png
PBB GE PCDH10 gnf1h01052 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 57575 18526
Ensembl ENSG00000138650 ENSMUSG00000049100
UniProt Q9P2E7 E9PX28
RefSeq (mRNA) NM_020815 NM_001098170
RefSeq (protein) NP_065866 NP_001091640
Location (UCSC) Chr 4:
134.07 – 134.13 Mb
Chr 3:
45.38 – 45.43 Mb
PubMed search [1] [2]

Protocadherin-10 is a protein that in humans is encoded by the PCDH10 gene.[1][2]

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The mRNA encodes a cadherin-related neuronal receptor thought to play a role in the establishment and function of specific cell-cell connections in the brain. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Alternatively spliced transcripts encode isoforms with unique cytoplasmic domains.[2]

References[edit]

  1. ^ Nollet F, Kools P, van Roy F (Jul 2000). "Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members". J Mol Biol 299 (3): 551–72. doi:10.1006/jmbi.2000.3777. PMID 10835267. 
  2. ^ a b "Entrez Gene: PCDH10 protocadherin 10". 

Further reading[edit]