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Phosphodiesterase 1B, calmodulin-dependent
Protein PDE1B PDB 1taz.png
PDB rendering based on 1taz.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols PDE1B ; PDE1B1; PDES1B
External IDs OMIM171891 MGI97523 HomoloGene37370 IUPHAR: 1295 ChEMBL: 4425 GeneCards: PDE1B Gene
EC number
RNA expression pattern
PBB GE PDE1B 206444 at tn.png
More reference expression data
Species Human Mouse
Entrez 5153 18574
Ensembl ENSG00000123360 ENSMUSG00000022489
UniProt Q01064 Q01065
RefSeq (mRNA) NM_000924 NM_008800
RefSeq (protein) NP_000915 NP_032826
Location (UCSC) Chr 12:
54.94 – 54.97 Mb
Chr 15:
103.5 – 103.53 Mb
PubMed search [1] [2]

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B is an enzyme that in humans is encoded by the PDE1B gene.[1][2][3]


  1. ^ Jiang X, Li J, Paskind M, Epstein PM (Nov 1996). "Inhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cells". Proc Natl Acad Sci U S A 93 (20): 11236–41. doi:10.1073/pnas.93.20.11236. PMC 1074519. PMID 8855339. 
  2. ^ Yu J, Wolda SL, Frazier AL, Florio VA, Martins TJ, Snyder PB, Harris EA, McCaw KN, Farrell CA, Steiner B, Bentley JK, Beavo JA, Ferguson K, Gelinas R (Feb 1998). "Identification and characterisation of a human calmodulin-stimulated phosphodiesterase PDE1B1". Cell Signal 9 (7): 519–29. doi:10.1016/S0898-6568(97)00046-6. PMID 9419816. 
  3. ^ "Entrez Gene: PDE1B phosphodiesterase 1B, calmodulin-dependent". 

Further reading[edit]